Geliko Gelatine in Pharmaceutical Applications
Geliko kosher pharmaceutical gelatine and gelatine hydrolysate are produced using the highest possible production standards under the most stringent of hygienic requirements. Geliko kosher gelatine products meet all conditions prescribed by current pharmacopoeias, as well as pharmaceutical industry standards.
Gelatine's many functionalities including...
· Film formation
· Neutral taste and aroma
· Low allergenic potential
· Variable dissolution rate
...make it a versatile ingredient for many kosher pharmaceutical formulations.
Gelatine capsules are one of the most convenient forms of encapsulation used for medicines and dietary supplements. Gelatine protects the capsule contents from the deleterious effects of atmospheric oxygen, light, moisture, and dust.
· Thermoreversible gelation
Gelatine-coated tablets are prepared using a special dipping process or by incorporation into premade hard or soft gelatine capsules.
Gelatine is a healthy and natural foodstuff that is approximately 90% protein. It contains no fat, carbohydrate, cholesterol, or preservatives.
There are observations and medical experiences on the positive effect of gelatine on skin, nails, hair and bones. Experimental findings and clinical studies carried out in the past two decades strongly suggest that gelatine hydrolysate may have a beneficial effect on joint health both in terms of prevention and therapy. Further studies have shown that osteoarthritis patients consuming gelatine hydrolysate experience significant pain reduction and subsequently, reduced consumption of analgesics.
Hard gelatine capsules are produced using high-Bloom gelatins, 200-260 Bloom, and can be produced in various sizes and colors. Hard gelatine capsules are manufactured using a "dipping process" that forms two separate capsule halves, "body" and "cap." Automated systems produce up to 40,000 capsules per hour by dipping polished stainless steel pins into a concentrated gelatine solution (25% to 35%) that is maintained at a constant temperature.
After drying, cutting, and assembling, the hard capsules are ready for filling with powder, granules, or liquids.
Soft gelatine capsules are easy to swallow, and dissolve readily in the body, improving the bioavailability of the active substance. Special coatings provide resistance to gastric juices, allowing developers to specify the time required for capsule dissolution. Medium-Bloom gelatine, 150- 200 Bloom, is used for the production of soft gelatine capsules.
Spherical or tube-shaped capsules are ideal for products intended for topical application. The contents can be easily squeezed out. Special soft gelatine capsules have also been developed for suppository products.